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What Causes Itching? What Helps with Itching? How Can It Be Treated?

Itching can arise from various conditions, including skin disorders such as eczema, allergic reactions to foods or medications, insect bites, hormonal imbalances, parasites like scabies, liver diseases, blood disorders such as lymphoma, and certain cancers. Additionally, systemic conditions like diabetes can also trigger itching. While most cases of itching are mild and temporary, persistent itching lasting several days should be evaluated by a medical professional to determine the underlying cause.

What Is Itching?

Itching is an unpleasant and sometimes overwhelming sensation that prompts the urge to scratch. It occurs when nerve endings in the skin are triggered by histamine, a chemical involved in immune responses. Itching is most commonly experienced on the scalp, arms, and legs, but in some cases, it may spread across the entire body.

To alleviate itching, consider taking cool or lukewarm showers, moisturizing the skin at least twice daily, applying cold compresses, using anti-itch creams or calamine lotion, applying aloe vera gel, wearing loose cotton clothing, and taking antihistamines when necessary.

What Causes Itching?

Itching can result from a variety of factors, including allergies, dry skin, infections, and underlying medical conditions. Some of the most common causes include:

  • Allergic reactions to foods, pollen, and medications
  • Parasitic infestations such as scabies, lice, or pinworms
  • Insect bites
  • Hormonal fluctuations
  • Skin disorders like eczema and psoriasis
  • Internal diseases affecting the liver, kidneys, or thyroid
  • Blood disorders and cancers, including lymphoma
  • Irritation from cosmetics and skincare products
  • Neurological disorders such as diabetes and shingles

Diabetes-related itching is often persistent and can be particularly intense in the genital area. Individuals experiencing this should consult a dermatologist. Additionally, diabetes can cause blisters or wounds on the skin, which should never be picked or popped.

What Diseases Cause Itching?

Certain medical conditions are known to contribute to chronic itching. These include:

  • Anxiety, depression, and stress
  • Diabetes mellitus
  • Pregnancy-related hormonal changes
  • Kidney, liver, and thyroid disorders
  • Skin conditions such as eczema, psoriasis, and dermatitis
  • Anemia
  • Cancers such as lymphoma and leukemia
  • Allergic reactions
  • Internal infections
  • Neurological disorders

Causes of Nighttime Itching

Many people experience increased itching at night, which can be severe enough to disturb sleep. This is more common among individuals over 65, those with sensitive or allergy-prone skin, people who shower excessively, and those with skin conditions like eczema or psoriasis. Pregnancy-related hormonal shifts can also contribute to nighttime itching.

Some key factors that cause nighttime itching include:

  • Autoimmune issues: The immune system may mistakenly attack healthy cells, leading to inflammation and itching.
  • Body temperature changes: During the night, body temperature naturally drops, and increased blood flow may trigger heat sensations that worsen itching.
  • Dry skin: The skin loses moisture at night, making itching more pronounced.
  • Hormonal fluctuations: Lower hormone levels at night can make the skin more susceptible to itching.
  • Environmental factors: Temperature and humidity levels in the room can impact skin hydration and irritation.

What Causes Itching During Pregnancy?

One of the main causes of pregnancy-related itching is a condition known as urticarial rash, which often occurs during first pregnancies. This typically develops around the 35th week of pregnancy and manifests as intense itching, particularly in areas with stretch marks. The skin may also develop red, raised bumps known as urticarial plaques.

Though the exact cause remains unclear, it is believed to be linked to skin stretching. While this condition does not harm the baby, if the itching becomes too severe, an early delivery may be considered. In most cases, the itching subsides naturally after childbirth.

What Helps with Itching?

Several remedies can help alleviate itching and provide relief:

  • Applying a cold, damp cloth or ice pack to the affected area
  • Moisturizing regularly to prevent dryness
  • Taking oral antihistamines
  • Using aloe vera gel or petroleum jelly
  • Wearing breathable clothing made of cotton or silk
  • Choosing fragrance-free lotions and skincare products
  • Washing the skin with baking soda-infused water
  • Supplementing with vitamins and minerals such as A, B12, omega-3, zinc, and iron

Avoiding scratching is crucial, as it can worsen the irritation and prolong the healing process.

How Is Itching Treated?

Treatment for itching depends on the underlying cause. Common approaches include:

  • Taking warm (not hot) showers
  • Applying cold compresses to the affected areas
  • Using creams, lotions, or medicated ointments
  • Taking antihistamines, steroids, or antifungal medications as prescribed
  • Wearing loose, cotton-based clothing
  • Managing stress levels
  • Opting for hypoallergenic, fragrance-free personal care products

If itching is heat-related, using sunscreen can help protect the skin from UV damage and prevent irritation.

For stress-induced itching, a dual approach involving both dermatological and psychiatric treatment may be necessary. Neurodermatitis, or stress-induced eczema, has become increasingly common and often requires care from both a dermatologist and a psychiatrist. Chronic stress and psychiatric disorders can contribute significantly to persistent itching.

Liver diseases, excessive alcohol consumption, and cirrhosis can also cause itching. The liver, along with the kidneys, is responsible for filtering toxins from the body. If bile cannot properly flow from the gallbladder due to blockages or pancreatic diseases, jaundice may develop, which can further exacerbate itching.

Topical creams, often containing cortisone, are commonly used to reduce itching. However, corticosteroids should be used under medical supervision, as improper use may worsen certain conditions. For example, fungal infections can cause itching, but using a cortisone-based cream on a fungal infection may relieve itching temporarily while allowing the fungus to spread.

Applying cold packs to itchy areas can help reduce symptoms by counteracting the effects of histamine.

Frequently Asked Questions About Itching

Why Does Cancer-Related Itching Occur?

Cancer cells release certain substances that trigger an immune response, leading to itching. This type of itching can be severe and is often localized to the legs or chest. Itching typically improves once the cancer is treated.

What Causes Itchy Legs?

Leg itching may be due to dry skin, allergies, skin conditions (such as eczema or psoriasis), insect bites, circulatory issues, hormonal fluctuations, nerve damage, diabetic neuropathy, folliculitis, or varicose veins.

Which Vitamin Deficiency Causes Itching?

Deficiencies in vitamin A and vitamin B12 can contribute to itchy skin. A blood test may help determine whether supplementation is needed.

What Causes Itching Without a Rash?

Itching without visible skin changes may be caused by dry skin, insect bites, kidney or liver disorders, or thyroid imbalances.

What Are the Causes of Nighttime Itching?

Night itching can be linked to eczema, psoriasis, thyroid dysfunction, diabetes, kidney disease, liver conditions, allergies, scabies, or even cancers such as leukemia. Changes in nighttime body temperature and moisture loss can also contribute.

When Should Persistent Itching Be a Concern?

If itching persists for more than two weeks despite home treatments, consulting a dermatologist is recommended.

What Foods Trigger Itching?

Common allergenic foods include peanuts, wheat, eggs, dairy, soy, and shellfish.

Why Does Itching Worsen at Night?

Psychological stress often triggers nighttime itching. During the day, distractions keep the mind occupied, but stress-related thoughts can intensify at night, leading to itching. Additionally, scabies is a common cause of nighttime itching.

How Is Neurodermatitis Treated?

Neurodermatitis treatment involves topical medications and antihistamines, particularly those with a sedative effect to improve sleep.

Does Scratching Make Itching Worse?

Yes. Scratching releases histamine, increasing inflammation and making the itching worse.

What Types of Cancer Cause Itching?

Cancers of the liver, gallbladder, pancreas, stomach, and prostate—particularly in elderly patients—can cause itching.

By addressing the root cause of itching, appropriate treatments can be implemented to provide relief and improve quality of life.

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