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Preimplantation Genetic Testing (PGT / PGS)

Ensure healthy pregnancies with advanced preimplantation genetic testing (PGT / PGS) at Erdem Hospital, where science and compassion come together to provide couples with peace of mind and improved fertility outcomes.

PGT at Erdem Hospital

For many couples undergoing IVF or ICSI, concerns about genetic disorders or chromosomal abnormalities are significant. Preimplantation Genetic Testing (PGT) previously known as Preimplantation Genetic Screening (PGS) offers a powerful solution. By analyzing embryos before transfer, PGT identifies genetic abnormalities that may lead to implantation failure, miscarriage, or inherited conditions.

At Erdem Hospital, this testing is integrated into IVF and ICSI cycles to ensure that only chromosomally healthy embryos are selected for transfer. This improves pregnancy rates, reduces the risk of miscarriage, and provides reassurance for couples with known genetic risks or a history of failed fertility treatments.

Turkey has become a preferred destination for international patients seeking PGT, combining advanced laboratory technology with affordability and comprehensive care.

Erdem Hospital & Healthcare Group

What’s Included in the PGT Journey

A complete PGT package at Erdem Hospital typically includes:

  • Fertility consultation and IVF/ICSI cycle planning. 
  • Ovarian stimulation and egg retrieval. 
  • Fertilization and embryo culture in the laboratory. 
  • Embryo biopsy for genetic analysis (performed on day 5/6 blastocysts). 
  • Advanced genetic testing for chromosomal abnormalities or specific hereditary conditions. 
  • Selection of healthy embryos for transfer or freezing. 
  • Hotel accommodation and VIP transfers between airport, hospital, and hotel. 
  • Multilingual staff and coordinators for international patients. 
  • Ongoing follow-up and consultation after results. 

This all-in-one approach ensures couples feel guided, supported, and reassured throughout the entire process.

PGT Prices Compared

The cost of PGT can vary widely across countries.

  • In the United States, adding PGT to an IVF cycle can cost between $5,000 and $10,000. At Erdem Hospital, PGT is available for under $3,500 when combined with an IVF cycle. 
  • In major European capitals such as London, Paris, or Berlin, patients can save up to 50–60% by choosing treatment in Istanbul, even after including flights and accommodation. 

This makes Turkey one of the most cost-effective destinations for advanced genetic fertility services.

PGT Process

The preimplantation genetic testing process at Erdem Hospital is integrated into the IVF cycle with careful precision:

  1. Consultation and IVF Planning: A detailed fertility and genetic consultation, followed by ovarian stimulation and egg retrieval. 
  2. Fertilization and Embryo Culture: Eggs are fertilized via IVF or ICSI, and embryos are cultured to the blastocyst stage. 
  3. Embryo Biopsy: A few cells are carefully removed from the outer layer of the embryo without harming development. 
  4. Genetic Analysis: Embryo cells are sent to the laboratory to test for chromosomal abnormalities (aneuploidy) or specific genetic conditions. 
  5. Embryo Selection: Only healthy embryos are chosen for transfer, significantly improving pregnancy outcomes. 
  6. Transfer or Freezing: Healthy embryos are either transferred in the same cycle or frozen for future use. 

This process typically extends the IVF timeline by a few days, but it greatly enhances safety and success.

What Patients Often Say After PGT

Couples who undergo PGT often share that the process gave them reassurance and reduced the emotional stress of uncertainty.

Some common reflections include:

  • “We had experienced miscarriages before, but PGT helped us finally achieve a healthy pregnancy.” 
  • “The hospital explained every step clearly, and we felt confident in our decision.” 
  • “Knowing that only healthy embryos were transferred gave us peace of mind we couldn’t have imagined before.” 

These voices underline how PGT is not only a medical advancement but also a source of emotional relief.

Frequently Asked Questions

What is the difference between PGT and PGS?
PGS is the older term for screening embryos for chromosomal abnormalities. Today, PGT is the broader term that includes both chromosomal screening (PGT-A) and testing for specific genetic conditions (PGT-M).

Who should consider PGT?
Couples with recurrent miscarriages, advanced maternal age, failed IVF attempts, or known hereditary conditions are ideal candidates.

Does PGT guarantee a healthy baby?
PGT reduces the risk of genetic abnormalities but cannot guarantee a healthy baby. It significantly increases the chances of successful pregnancy.

Is embryo biopsy safe?
Yes, when performed by experienced specialists, embryo biopsy is considered safe and does not harm the embryo’s ability to implant and grow.

How many embryos are usually tested?
The number depends on ovarian response and fertilization success. Multiple embryos can be tested in a single cycle.

Can frozen embryos be tested later?
Yes, previously frozen embryos can be thawed, biopsied, and refrozen for genetic testing.

Erdem Hospital & Healthcare Group

Advancing Fertility with Preimplantation Genetic Testing (PGT)

For couples embarking on the journey to parenthood through assisted reproductive technologies, the hope of achieving a healthy pregnancy is often accompanied by understandable concerns. Questions about genetic health, potential risks, and the chances of miscarriage weigh heavily on many families. Preimplantation Genetic Testing (PGT) has emerged as one of the most significant innovations in fertility care, offering reassurance, precision, and peace of mind.

At Erdem Hospital, PGT is seamlessly integrated into IVF and ICSI treatments. Guided by over 37 years of medical expertise, this advanced service ensures that embryos can be tested for genetic health before transfer, giving couples the confidence that they are taking every step possible toward achieving a safe and successful pregnancy. By combining science with compassion and accessibility, Erdem Hospital empowers families from all over the world to move forward with clarity and hope.

What Is Preimplantation Genetic Testing?

Preimplantation Genetic Testing, or PGT, is a procedure performed during an IVF or ICSI cycle that screens embryos for genetic abnormalities before they are transferred to the uterus. By identifying embryos with normal chromosome numbers or specific genetic characteristics, PGT significantly reduces the risk of miscarriage and increases the chances of delivering a healthy baby.

Modern PGT relies on sophisticated laboratory techniques, allowing embryologists to examine embryos at a cellular level. A few cells are carefully biopsied from the embryo on the fifth or sixth day of development, then analyzed using advanced genetic technologies. Importantly, this process does not damage the embryo, which can be safely frozen and later transferred once results are confirmed.

Types of PGT

There are different forms of PGT, each addressing specific concerns:

  • PGT-A (Aneuploidy Screening): Tests embryos for abnormal chromosome numbers, which are a common cause of miscarriage and failed implantation. 
  • PGT-M (Monogenic Disease Testing): Screens embryos for single-gene disorders, such as cystic fibrosis, Huntington’s disease, or sickle cell anemia, particularly when one or both parents are known carriers. 
  • PGT-SR (Structural Rearrangements): Detects chromosomal rearrangements, such as translocations or inversions, which may lead to infertility or miscarriage. 

By tailoring the type of PGT to each couple’s medical background, fertility specialists at Erdem Hospital ensure the most effective and appropriate testing pathway is chosen.

Who Can Benefit from PGT?

PGT is not limited to a specific group of patients; it is a valuable option for many couples pursuing assisted reproduction. The most common candidates include:

  • Couples with Recurrent Miscarriages: PGT helps identify chromosomally normal embryos, reducing the risk of another loss. 
  • Older Mothers: Women over the age of 35 face higher risks of chromosomal abnormalities, making PGT an important tool to increase pregnancy success. 
  • Couples with Genetic Disorders: Those who carry known genetic conditions can use PGT-M to prevent passing them on to children. 
  • Previous IVF or ICSI Failures: PGT can explain why embryos may not have implanted and guide more successful future cycles. 
  • Couples Using Donor Gametes: Even with donor eggs or sperm, PGT provides reassurance by ensuring the healthiest embryos are transferred. 

This broad scope makes PGT one of the most versatile tools in fertility medicine, offering hope to couples who may otherwise feel uncertain about their prospects.

The PGT Process Step by Step

At Erdem Hospital, the PGT journey is designed to be transparent and supportive, ensuring patients understand each stage of the process.

  1. IVF or ICSI Cycle – Eggs are retrieved from the woman and fertilized with sperm in the laboratory to create embryos. 
  2. Embryo Culture – Embryos are grown in a carefully controlled environment for five to six days until they reach the blastocyst stage. 
  3. Embryo Biopsy – A few cells are gently removed from the trophectoderm (the outer layer of the embryo) under a high-powered microscope. 
  4. Genetic Analysis – The biopsied cells are analyzed in a specialized genetics laboratory to identify chromosomal or genetic abnormalities. 
  5. Embryo Freezing – Embryos are cryopreserved using vitrification while awaiting results. 
  6. Embryo Transfer – Chromosomally normal or genetically healthy embryos are thawed and transferred into the uterus at the optimal time for implantation. 

By combining meticulous laboratory practices with advanced genetic technology, Erdem Hospital ensures that the PGT process is both safe and effective.

Benefits of PGT

PGT offers multiple advantages that extend beyond traditional IVF or ICSI outcomes:

  • Reduced Risk of Miscarriage: By transferring only chromosomally normal embryos, the likelihood of pregnancy loss decreases significantly. 
  • Improved Implantation Rates: Healthy embryos are more likely to implant successfully, increasing the overall success rate of IVF or ICSI. 
  • Fewer Failed Cycles: Patients may avoid the emotional and financial strain of repeated failed attempts. 
  • Genetic Reassurance: Couples with hereditary conditions can make informed decisions and prevent the transmission of genetic diseases. 
  • Family Planning Confidence: Patients gain clarity about the health of their embryos before starting a pregnancy, reducing uncertainty and stress. 

These benefits demonstrate why PGT is increasingly recommended in fertility centers worldwide as a cornerstone of modern reproductive care.

Emotional Considerations of PGT

While PGT offers profound advantages, the emotional journey of couples undergoing testing is equally important. The decision to screen embryos can bring a sense of relief but also raise new questions. Will there be enough healthy embryos? What if results are unexpected?

At Erdem Hospital, emotional support is integrated into every stage of treatment. Fertility specialists take time to explain results, guide couples through decision-making, and provide reassurance during what can be a highly sensitive process. By addressing both the medical and emotional dimensions, patients feel empowered to move forward with confidence.

Why Experience Matters in PGT

The accuracy and safety of PGT depend heavily on the expertise of the medical and laboratory team. Embryo biopsy requires delicate precision, and genetic analysis must be interpreted correctly to ensure reliable outcomes.

Erdem Hospital brings over 37 years of expertise in reproductive medicine, combining skilled embryologists, advanced laboratories, and internationally recognized fertility specialists. This wealth of experience ensures that patients receive world-class standards of care while benefiting from a supportive and compassionate environment.

PGT and the Future of Fertility

As reproductive technology continues to advance, PGT is becoming increasingly central to fertility care. Beyond its current applications, researchers are exploring ways to integrate even more sophisticated genetic insights, potentially identifying embryo health at a deeper level.

For couples today, however, the impact of PGT is already transformative. By combining IVF or ICSI with genetic screening, they gain not only higher chances of success but also the reassurance that their journey is grounded in science, safety, and informed choice.

A Clear Path to Parenthood

Preimplantation Genetic Testing is more than a laboratory procedure it is a tool of empowerment. It gives couples reassurance that they are making the best possible decisions for their future family. Whether used to reduce miscarriage risk, avoid passing on genetic conditions, or increase the success of IVF and ICSI, PGT represents clarity and confidence in a journey often filled with uncertainty.

At Erdem Hospital, every PGT cycle is guided by precision, compassion, and over three decades of expertise. By integrating advanced science with patient-centered care, the hospital provides couples from around the world with the opportunity to move forward on their path to parenthood with renewed hope and trust.